Minggu, 12 September 2010
Research on Ashitaba and Cancer
In vitro induction of the anticarcinogenic marker enzyme, quinone reductase, in human hepatoma cells by food extracts.
Hashimoto K, Kawamata S, Usui N, Tanaka A, Uda Y. Cancer Lett. 2002 Jun 6;180(1):1-5.
Anti-tumor-promotion by principles obtained from Angelica keiskei. Okuyama T, Takata M, Takayasu J, Hasegawa T, Tokuda H, Nishino A, Nishino H, Iwashima A. Planta Med. 1991 Jun;57(3):242-6.
Potent antimitotic and cell growth inhibitory properties of substituted chalcones, S. Ducki, R. Forrest, et al.,. Med. Chem. Lett., 1998, 8, 1051.
Ashitaba Helps to Inhibit Cancer: Linked Parallel Synthesis and MTT Bioassay Screening of Substituted Chalcones, N. J. Lawrence, D. Rennison, A. T. et al., Chem., 2001, 3, in press.
The Interaction of Chalcones with Tubulin, N. J. Lawrence, A. T. McGown, S. Ducki and J. A. Hadfield, Anticancer Drug Design, 2000, 15, 135.
Effect of naturally occurring coumarins on the formation of epidermal DNA adducts and skin tumors induced by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in SENCAR mice. Cai Y, Kleiner H, Johnston D, Dubowski A, Bostic S, Ivie W, DiGiovanni J.
Isobavachalcone, a Chalcone Constituent of Angelica keiskei, Induces Apoptosis in Neuroblastoma. Nishimura R, Tabata K, Arakawa M, Ito Y, Kimura Y, Akihisa T, Nagai H, Sakuma A, Kohno H, Suzuki T. Biol Pharm Bull. 2007 Oct;30(10):1878-83.
Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells. Tabata K, Motani K, Takayanagi N, Nishimura R, Asami S, Kimura Y, Ukiya M, Hasegawa D, Akihisa T, Suzuki T. Biol Pharm Bull. 2005 Aug;28(8):1404-7. PMID: 16079483 [PubMed - indexed for MEDLINE]
Antitumor and antimetastatic activities of 4-hydroxyderricin isolated from Angelica keiskei roots.Kimura Y, Taniguchi M, Baba K. Planta Med. 2004 Mar;70(3):211-9. PMID: 15114497 [PubMed - indexed for MEDLINE]
Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects. Akihisa T, Tokuda H, Hasegawa D, Ukiya M, Kimura Y, Enjo F, Suzuki T, Nishino H. J Nat Prod. 2006 Jan;69(1):38-42 - - inhibitory effects on the induction of Epstein-Barr virus, - - inhibitory effects on skin tumor promotion
Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects. Akihisa T, Tokuda H, Ukiya M, Iizuka M, Schneider S, Ogasawara K, Mukainaka T, Iwatsuki K, Suzuki T, Nishino H. Cancer Lett. 2003 Nov 25;201(2):133-7 - - antitumor-promoters
In vitro induction of the anticarcinogenic marker enzyme, quinone reductase, in human hepatoma cells by food extracts.
Hashimoto K, Kawamata S, Usui N, Tanaka A, Uda Y. Cancer Lett. 2002 Jun 6;180(1):1-5.
Anti-tumor-promotion by principles obtained from Angelica keiskei. Okuyama T, Takata M, Takayasu J, Hasegawa T, Tokuda H, Nishino A, Nishino H, Iwashima A. Planta Med. 1991 Jun;57(3):242-6.
Potent antimitotic and cell growth inhibitory properties of substituted chalcones, S. Ducki, R. Forrest, et al.,. Med. Chem. Lett., 1998, 8, 1051.
Ashitaba Helps to Inhibit Cancer: Linked Parallel Synthesis and MTT Bioassay Screening of Substituted Chalcones, N. J. Lawrence, D. Rennison, A. T. et al., Chem., 2001, 3, in press.
The Interaction of Chalcones with Tubulin, N. J. Lawrence, A. T. McGown, S. Ducki and J. A. Hadfield, Anticancer Drug Design, 2000, 15, 135.
Effect of naturally occurring coumarins on the formation of epidermal DNA adducts and skin tumors induced by benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene in SENCAR mice. Cai Y, Kleiner H, Johnston D, Dubowski A, Bostic S, Ivie W, DiGiovanni J.
Isobavachalcone, a Chalcone Constituent of Angelica keiskei, Induces Apoptosis in Neuroblastoma. Nishimura R, Tabata K, Arakawa M, Ito Y, Kimura Y, Akihisa T, Nagai H, Sakuma A, Kohno H, Suzuki T. Biol Pharm Bull. 2007 Oct;30(10):1878-83.
Xanthoangelol, a major chalcone constituent of Angelica keiskei, induces apoptosis in neuroblastoma and leukemia cells. Tabata K, Motani K, Takayanagi N, Nishimura R, Asami S, Kimura Y, Ukiya M, Hasegawa D, Akihisa T, Suzuki T. Biol Pharm Bull. 2005 Aug;28(8):1404-7. PMID: 16079483 [PubMed - indexed for MEDLINE]
Antitumor and antimetastatic activities of 4-hydroxyderricin isolated from Angelica keiskei roots.Kimura Y, Taniguchi M, Baba K. Planta Med. 2004 Mar;70(3):211-9. PMID: 15114497 [PubMed - indexed for MEDLINE]
Chalcones and other compounds from the exudates of Angelica keiskei and their cancer chemopreventive effects. Akihisa T, Tokuda H, Hasegawa D, Ukiya M, Kimura Y, Enjo F, Suzuki T, Nishino H. J Nat Prod. 2006 Jan;69(1):38-42 - - inhibitory effects on the induction of Epstein-Barr virus, - - inhibitory effects on skin tumor promotion
Chalcones, coumarins, and flavanones from the exudate of Angelica keiskei and their chemopreventive effects. Akihisa T, Tokuda H, Ukiya M, Iizuka M, Schneider S, Ogasawara K, Mukainaka T, Iwatsuki K, Suzuki T, Nishino H. Cancer Lett. 2003 Nov 25;201(2):133-7 - - antitumor-promoters
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